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Patients presenting with symptoms of acute ischemic stroke who have evidence of large vessel (> 2.5mm in diameter) occlusion in the cerebral circulation will be assigned to either the Penumbra System with the Separator 3D or the Penumbra System without the Separator 3D. The hypothesis to be tested is that the safety and effectiveness of the Penumbra system with the Separator 3D for the revascularization of large vessel occlusion is not inferior to the Penumbra System alone.
A prospective multi-center study of patients with intracranial aneurysms, peripheral aneurysms or other malformations who are treated by the PC 400 system.
A Phase III Randomized Multicenter Clinical Trial of Blood Pressure Reduction for Hypertension in Acute Intracerebral Hemorrhage.
The objective of this study is to determine the long-term effects of lysing ventricular blood clots with rT-PA on functional outcomes of cerebral hemorrhage patients.
The purpose of the study is to understand whether a new treatment of stroke - endovascular clot removal - can be added to the current standard of care to improve patient outcomes.
The purpose of this study is to determine whether the combination of thrombolysis and hypothermia is superior to thrombolysis alone for the treatment of ischemic stroke.
A phase III, randomized, case-controlled, open-label, 500-subject clinical trial of minimally invasive surgery plus rt-PA in the treatment of intracerebral hemorrhage (ICH).
A descriptive pilot study that aims to evaluate the changes in the patient’s neurologic and cognitive function following surgical treatment for Moyamoya disease. Pre-treatment and post-treatment evaluations of the patients’ neurologic function and status, cognitive and psychological functioning and imaging studies will be performed. The aim is to gain a better understanding of the cognitive and functional impact of Moyamoya disease after surgical intervention.
An interventional registry to collect real world, post-marketing data on the use of Stryker Target® 360° and Target® 2D coils for the embolization of ruptured or unruptured intracranial saccular aneurysms. A post hoc analysis comparing Target® 360° and Target® 2D coil technical and clinical endpoints will be performed.
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